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Int J Mol Sci. 2017 Mar 11;18(3). pii: E615. doi: 10.3390/ijms18030615.

Cellular Midpalatal Suture Changes after Rapid Maxillary Expansion in Growing Subjects: A Case Report.

Author information

1
Department of Surgical and Morphological Sciences, University of Insubria, 21100 Varese, Italy. alberto.caprioglio@uninsubria.it.
2
Department of Medical, Surgical and Health Sciences, University of Messina, 98100 Messina, Italy. rosamariaf@hotmail.it.
3
Department of Surgical and Morphological Sciences, University of Insubria, 21100 Varese, Italy. pieroantonio@gmail.com.
4
Department of Surgical and Morphological Sciences, University of Insubria, 21100 Varese, Italy. teoberet@libero.it.
5
Department of Medical, Oral and Biotechnological Sciences, University of Chieti-Pescara, 66100 Chieti, Italy. camangan@gmail.com.
6
Department of Medical, Oral and Biotechnological Sciences, University of Chieti-Pescara, 66100 Chieti, Italy. apiattelli@unich.it.
7
Department of Surgical and Morphological Sciences, University of Insubria, 21100 Varese, Italy. aldo.macchi@uninsubria.it.
8
Department of Medical, Oral and Biotechnological Sciences, University of Chieti-Pescara, 66100 Chieti, Italy. gio.iezzi@unich.it.

Abstract

The present case report aimed to investigate immediate histologic changes in midpalatal suture in humans following rapid maxillary expansion compared to control. Three patients (mean age 8.3 +/- 0.9 years) were enrolled in the case report and underwent midpalatal suture biopsy. Two patients underwent treatment before biopsy. The third patient did not show transversal maxillary deficiency and was enrolled as a control. Biopsy samples of midpalatal suture at 7 (subject 1) and 30 days (subject 2) after maxillary expansion as well as of one control (subject 3) were collected and processed for histology. In the control (subject 3) inter-digitations at the palatal suture gap were observed. At 7 days (subject 1) mature bone with small marrow spaces and trabecular bone with the peculiar storiform appearance inside the soft tissue and collagen fibers running parallel only in the central part were present. At 30 days (subject 2), a greater number of newly-formed bone trabeculae with a perpendicular orientation to the long axis of the suture could be seen. At 30 days the fibrous component of bone tissue was less represented compared to the sample at 7 days. Data from the preliminary histological results showed that bone formation was observed in the gap after rapid maxillary expansion, although the healing process was still ongoing.

KEYWORDS:

maxillary expansion; suture; treatment

PMID:
28287481
PMCID:
PMC5372631
DOI:
10.3390/ijms18030615
[Indexed for MEDLINE]
Free PMC Article

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