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J Virol. 1988 Mar;62(3):1093-6.

Specific amino acid substitutions are not required for transformation by v-myb of avian myeloblastosis virus.

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1
Department of Pathology, University of California, San Diego, La Jolla 92093.

Abstract

The protein product of the v-myb oncogene of avian myeloblastosis virus, p48v-myb, differs structurally in several ways from its normal cellular homolog, p75c-myb. We demonstrated that the 11 specific amino acid substitutions found in two independent molecular clones of this virus were not required for the transformation of myeloblasts by v-myb.

PMID:
2828660
PMCID:
PMC253675
[Indexed for MEDLINE]
Free PMC Article
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