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J Urol. 2017 Aug;198(2):401-406. doi: 10.1016/j.juro.2017.03.045. Epub 2017 Mar 10.

Intermediate-Term Outcomes and Complications of Long Segment Urethroplasty with Lingual Mucosa Grafts.

Author information

1
Department of Urology, Shanghai Jiaotong University Affiliated Sixth People's Hospital and Shanghai Eastern Urological Reconstruction and Repair Institute (YMX, HX, YLS, QF, JZ, CF, CRJ, LJS, HBL), Shanghai, China; Department of Urology, Tongji Hospital, Tongji University School of Medicine, Shanghai, China. Electronic address: xuyueminxu@163.com.
2
Department of Urology, Shanghai Jiaotong University Affiliated Sixth People's Hospital and Shanghai Eastern Urological Reconstruction and Repair Institute (YMX, HX, YLS, QF, JZ, CF, CRJ, LJS, HBL), Shanghai, China; Department of Urology, Tongji Hospital, Tongji University School of Medicine, Shanghai, China.

Abstract

PURPOSE:

We evaluated outcomes and donor site complications in male patients with complex urethral strictures who underwent urethroplasty using with long strip oral mucosal grafts. We also analyzed whether a lingual mucosa graft is a good substitute for repairing long segment urethral strictures.

MATERIALS AND METHODS:

This retrospective study was done in 81 male patients with complex urethral strictures who underwent oral mucosal graft urethroplasty. Patients with long segment (8 cm or greater) anterior urethral strictures who were considered candidates for long strip lingual mucosa graft urethroplasty were included in study.

RESULTS:

Oral mucosal graft urethroplasty was performed in 81 patients with complex urethral strictures between August 2006 and December 2014. Mean urethral stricture length was 12.1 cm (range 8 to 20). A single 9 to 12 cm long strip lingual mucosa graft was used in 52 patients, a lingual mucosa graft greater than 12 cm was placed in 17 and a lingual mucosa graft combined with a buccal mucosal graft was used in 12. Mean followup was 41 months (range 15 to 86) postoperatively. The overall urethroplasty success rate was 82.7%. Urethral complications developed in 14 patients (17.3%), including urethral strictures in 10 and urethrocutaneous fistulas in 4. At 12 months 5 patients (6.2%) reported minimal difficulty with fine motor movement of the tongue.

CONCLUSIONS:

Lingual mucosa harvested from the ventrolateral surface of the tongue can provide a wide and long graft that is an excellent urethral substitute. Donor site complications are primarily limited to postoperative year 1. Our study confirms that the lingual mucosa graft is a good substitute for urethral reconstruction and lingual mucosa graft urethroplasty is a valuable procedure to treat long anterior urethral strictures.

KEYWORDS:

autologous; lichen sclerosus et atrophicus; mouth mucosa; tongue; transplantation; urethral stricture

PMID:
28286073
DOI:
10.1016/j.juro.2017.03.045
[Indexed for MEDLINE]

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