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Ageing Res Rev. 2017 Jul;36:42-49. doi: 10.1016/j.arr.2017.02.006. Epub 2017 Mar 8.

Cognitive functioning of individuals aged 90 years and older without dementia: A systematic review.

Author information

1
Alzheimer Center & Department of Neurology, Neuroscience Campus Amsterdam, VU University Medical Center, Amsterdam, The Netherlands. Electronic address: n.legdeur@vumc.nl.
2
Department of Clinical Neuropsychology, Vrije Universiteit Amsterdam, The Netherlands.
3
Medical Library, Vrije Universiteit Amsterdam, The Netherlands.
4
Alzheimer Center & Department of Neurology, Neuroscience Campus Amsterdam, VU University Medical Center, Amsterdam, The Netherlands.
5
Alzheimer Center & Department of Neurology, Neuroscience Campus Amsterdam, VU University Medical Center, Amsterdam, The Netherlands; Department of Psychiatry & Neuropsychology, School for Mental Health and Neuroscience, Maastricht University, Maastricht, The Netherlands.
6
Department of Medicine and Aged Care, Royal Melbourne Hospital, University of Melbourne, Melbourne, Australia; MOVE Research Institute Amsterdam, Faculty of Human Movement Sciences, Vrije Universiteit Amsterdam, The Netherlands.

Abstract

INTRODUCTION:

Reference values to define cognitive impairment in individuals aged 90 years and older are lacking. We systematically reviewed the literature to determine the level of cognitive functioning of individuals aged 90 years and older without dementia.

METHODS:

The search identified 3972 articles of which 20 articles were included in the review. We calculated mean cognitive test scores and cut-off scores for cognitive tests published in two or more articles.

RESULTS:

The mean cognitive test scores (SD)/cut-off scores for individuals aged 90 years and older without dementia of the five most commonly used cognitive tests were: MMSE: 26.6 (2.6)/23.3 points, Digit Span forward: 5.9 (1.8)/3.6 digits, Digit Span backward: 4.4 (1.6)/2.4 digits, TMT-A: 85.8 (42.5)/140.2s and TMT-B: 220.3 (99.2)/347.3s.

DISCUSSION:

We provided mean cognitive test scores and cut-off scores that will improve the diagnostic process of cognitive impairment in individuals aged 90 years and older.

KEYWORDS:

Cognitive functioning; Cognitive impairment; Healthy ageing; Individuals aged 90 years and older; Nonagenarians; Reference values

PMID:
28284872
DOI:
10.1016/j.arr.2017.02.006
[Indexed for MEDLINE]

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