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BMC Cancer. 2017 Mar 10;17(1):185. doi: 10.1186/s12885-017-3156-1.

Radiofrequency ablation for liver metastases in patients with gastric cancer as an alternative to hepatic resection.

Author information

1
Department of Surgery, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, South Korea.
2
Present Address: Department of Surgery, Chuncheon Sacred Heart Hospital, College of Medicine, The Hallym University of Korea, Chuncheon, South Korea.
3
Department of Radiology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, South Korea.
4
Department of Surgery, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, South Korea. chpark@catholic.ac.kr.
5
Division of Gastrointestinal Surgery, Department of Surgery, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, 505 Banpo-dong, Seocho-gu, Seoul, 137-701, South Korea. chpark@catholic.ac.kr.

Abstract

BACKGROUND:

The purpose of this retrospective study was to determine whether RFA could provide an alternative treatment modality for selected patients who are not candidates for hepatic resection.

METHODS:

A total of 18 consecutive patients with liver metastases alone from gastric cancer treated with radiofrequency ablation (RFA, n = 11) or hepatic resection (HR, n = 7) at Seoul St. Mary's Hospital, Korea, between January 2000 and September 2014, were enrolled.

RESULTS:

The median OS and DFS in the RFA group were 40.5 ± 22.3 and 10.3 ± 1.07 months, respectively. There was no significant difference between the RFA and HR groups in terms of baseline characteristics except for performance status. Mean survival and DFS times of all patients were 60.1 ± 9.4 and 40.9 ± 10.2 months, respectively. Mean OS times in the HR and RFA groups were 67.5 ± 15.4 and 51.1 ± 9.8 months (P = 0.671), respectively, and the mean DFS time in the HR group (74.1 ± 14.2 months) was longer than that in the RFA group (26.9 ± 9.2 months), but the difference was not significant (P = 0.076).

CONCLUSIONS:

In patients who are not candidates for surgical treatment, RFA may be an alternative to HR.

KEYWORDS:

Gastric cancer; Liver metastases; Radiofrequency ablation

PMID:
28283024
PMCID:
PMC5345207
DOI:
10.1186/s12885-017-3156-1
[Indexed for MEDLINE]
Free PMC Article

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