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Cell Host Microbe. 2017 Mar 8;21(3):278-281. doi: 10.1016/j.chom.2017.02.021.

Microbes and Diet-Induced Obesity: Fast, Cheap, and Out of Control.

Author information

1
Department of Microbiology and Immunology, G.W. Hooper Research Foundation, University of California, San Francisco, 513 Parnassus Avenue, San Francisco, CA 94143, USA. Electronic address: peter.turnbaugh@ucsf.edu.

Abstract

Here I revisit our early experiments published in Cell Host & Microbe (Turnbaugh et al., 2008) showing that a diet rich in fat and simple sugars alters the gut microbiome in a manner that contributes to host adiposity, and reflect upon the remarkable advances and remaining challenges in this field.

KEYWORDS:

cellular memory; diet-induced obesity; gut microbiome; high-fat and high-sugar diets; metabolic disease; metagenomics; metatranscriptomics; microbial dynamics; multi-omics; nutrition

PMID:
28279330
PMCID:
PMC5751949
DOI:
10.1016/j.chom.2017.02.021
[Indexed for MEDLINE]
Free PMC Article

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