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J Allergy Clin Immunol. 2017 Aug;140(2):603-605. doi: 10.1016/j.jaci.2017.01.034. Epub 2017 Mar 6.

The benzene metabolite 1,4-benzoquinone reduces regulatory T-cell function: A potential mechanism for tobacco smoke-associated atopic dermatitis.

Author information

1
Department of Environmental Immunology, Helmholtz Centre for Environmental Research - UFZ, Leipzig, Germany.
2
Division of Theoretical Bioinformatics, German Cancer Research Center (DKFZ), Heidelberg, Germany; Heidelberg Center for Personalized Oncology (DKFZ-HIPO), Heidelberg, Germany.
3
Department of Ecological Chemistry, Helmholtz Centre for Environmental Research - UFZ, Leipzig, Germany; Technical University Bergakademie Freiberg, Freiberg, Germany.
4
Department of Environmental Immunology, Helmholtz Centre for Environmental Research - UFZ, Leipzig, Germany; La Jolla Institute for Allergy and Immunology, La Jolla, Calif.
5
Department of Molecular Systems Biology, Helmholtz Centre for Environmental Research - UFZ, Leipzig, Germany; Faculty of Biosciences, Pharmacy and Psychology, Department of Biochemistry, University of Leipzig, Leipzig, Germany.
6
Department of Environmental Microbiology, Helmholtz Centre for Environmental Research - UFZ, Leipzig, Germany.
7
Epiontis GmbH, Berlin, Germany.
8
Municipal Hospital "St Georg" Children's Hospital, Leipzig, Germany.
9
Division of Theoretical Bioinformatics, German Cancer Research Center (DKFZ), Heidelberg, Germany; Heidelberg Center for Personalized Oncology (DKFZ-HIPO), Heidelberg, Germany; Institute of Pharmacy and Molecular Biotechnology (IPMB), and BioQuant Center, University of Heidelberg, Heidelberg, Germany; Translational Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), University of Heidelberg, Heidelberg, Germany.
10
Department of Environmental Immunology, Helmholtz Centre for Environmental Research - UFZ, Leipzig, Germany. Electronic address: saskia.trump@ufz.de.
PMID:
28274748
DOI:
10.1016/j.jaci.2017.01.034
[Indexed for MEDLINE]
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