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Acta Orthop. 2016 Dec;87(sup363):1-5. doi: 10.1080/17453674.2017.1297918. Epub 2017 Mar 8.

Aarhus Regenerative Orthopaedics Symposium (AROS).

Author information

1
a Orthopaedic Research Laboratory , Aarhus University Hospital , Denmark.
2
b Department of Orthopaedics , Aarhus University Hospital , Denmark.
3
c Department of Large Animal Science , University of Copenhagen , Denmark.
4
d Division of Biochemistry, Faculty of Medicine , University of Oslo , Norway.
5
e Department of Orthopaedics , Sahlgrenska University Hospital, University of Gothenburg , Sweden.
6
f Department of Orthopaedics , University of Pennsylvania , PN , USA.
7
g Molecular Endocrinology and Stem Cell Research Unit (KMEB), University of Southern Denmark , Denmark.
8
h INSERM UMRS U791, University of Nantes , France.
9
i Department of Biomedicine , Aarhus University and Department of Rheumatology, Aarhus University Hospital , Denmark.
10
j Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDORMS) , University of Oxford , UK.
11
k Cartilage Restoration Center of Indiana , OrthoIndy , IN , USA.
12
l Cartilage Repair Center , Brigham and Women's Hospital, Harvard Medical School , Boston , MA , USA.
13
m Department of Orthopaedic Surgery, Yong Loo Lin School of Medicine , National University of Singapore , Singapore.
14
n Department of Orthopaedics , Akershus University Hospital and Institute of Health and Society, University of Oslo , Norway.
15
o Department of Biomedical Sciences , University of Guelph , ON , Canada.
16
p Department of Orthopaedics , Copenhagen University Hospital , Bispebjerg , Denmark.
17
q Comparative Medicine Lab, Aarhus University , Denmark.
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r Department of Engineering , Aarhus University , Denmark.
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s Robert Jones and Agnes Hunt Orthopaedic Hospital, Keele University , Oswestry , UK.
20
t Department of Orthopaedics , Tokai University Hospital , Japan.
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u Faculty of Dentistry , National University of Singapore , Singapore.
22
v Department of Physiology, Anatomy and Genetics , University of Oxford , UK.
23
w Department of Orthopaedics , Brigham and Women's Hospital, Harvard Medical School and Tissue Engineering Labs, VA Boston Healthcare System , Boston , MA , USA.

Abstract

The combination of modern interventional and preventive medicine has led to an epidemic of ageing. While this phenomenon is a positive consequence of an improved lifestyle and achievements in a society, the longer life expectancy is often accompanied by decline in quality of life due to musculoskeletal pain and disability. The Aarhus Regenerative Orthopaedics Symposium (AROS) 2015 was motivated by the need to address regenerative challenges in an ageing population by engaging clinicians, basic scientists, and engineers. In this position paper, we review our contemporary understanding of societal, patient-related, and basic science-related challenges in order to provide a reasoned roadmap for the future to deal with this compelling and urgent healthcare problem.

PMID:
28271925
PMCID:
PMC5389427
DOI:
10.1080/17453674.2017.1297918
[Indexed for MEDLINE]
Free PMC Article

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