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J Dermatolog Treat. 2017 Nov;28(7):574-581. doi: 10.1080/09546634.2017.1303571. Epub 2017 Mar 23.

Platelet rich plasma for treatment of non-scarring hair loss: systematic review of literature.

Author information

1
a Center for Research and Training in Skin diseases and Leprosy, Tehran University of Medical Science , Tehran , Iran.
2
b Clinical Trial Center, Tehran University of Medical Science , Tehran , Iran.
3
c Iranian National Center for Addiction Studies, Tehran University of Medical Science , Tehran , Iran.

Abstract

BACKGROUND:

Although there are many studies showing the role of platelet rich plasma (PRP) in bone grafts, teeth osteosynthesis, and wound healing, there have been little peer reviewed studies about the safety and efficacy of PRP application in the treatment of hair loss.

MATERIALS AND METHODS:

In this systematic review, we searched Ovid Medline, Scopus and Web of Knowledge till November 2015 for human studies evaluating the efficacy of PRP for the treatment of non-cicatricial alopecia.

RESULTS:

Among 704 articles retrieved in first search, 18 articles matched our inclusion criteria, 14 for androgenic alopecia and four for alopecia areata. They included two case reports, eight case series, six controlled clinical trials and only two randomized controlled trials.

CONCLUSIONS:

Most of the available evidence has shown low quality and controversial results about the efficacy of PRP in treating non-cicatricial alopecias, including androgenetic alopecia and alopecia areata. Further randomized controlled studies with more sample size and standard protocols regarding the number and interval of treatment sessions, number of platelets, method of activation, etc., are required to investigate the efficacy and safety of PRP in treating hair loss.

KEYWORDS:

PRP; alopecia areata; androgenetic alopecia; non-scarring alopecia

PMID:
28271918
DOI:
10.1080/09546634.2017.1303571
[Indexed for MEDLINE]

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