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Mol Imaging Biol. 2017 Jun;19(3):357-362. doi: 10.1007/s11307-017-1054-1.

Optical Surgical Navigation for Precision in Tumor Resections.

Author information

1
Department of Pediatrics, Stanford University, Stanford, CA, USA.
2
Department of Otolaryngology-Head and Neck Surgery, Stanford University, Stanford, CA, USA.
3
Department of Radiology, The Wright Center for Innovation in Biomedical Imaging, The Ohio State University College of Medicine, Columbus, OH, USA.
4
Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH, USA.
5
Department of Radiology, Case Western Reserve University, Cleveland, OH, USA.
6
National Foundation for Cancer Research Center for Molecular Imaging, Case Western Reserve University, Cleveland, OH, USA.
7
Department of Otolaryngology-Head and Neck Surgery and Radiology, Stanford University, Stanford, CA, USA. elr@stanford.edu.
8
Ann and John Doerr Medical Director, Stanford Cancer Center, Stanford, CA, USA. elr@stanford.edu.

Abstract

Optical imaging methods have significant potential as effective intraoperative tools to visualize tissues, cells, and biochemical events aimed at objective assessment of the tumor margin and guiding the surgeon to adequately resect the tumor while sparing critical tissues. The wide variety of approaches to guide resection, the range of parameters that they detect, and the interdisciplinary nature involving biology, chemistry, engineering, and medicine suggested that there was a need for an organization that could review, discuss, refine, and help prioritize methods to optimize patient care and pharmaceutical and instrument development. To address these issues, the World Molecular Imaging Society created the Optical Surgical Navigation (OSN) interest group to bring together scientists, engineers, and surgeons to develop the field to benefit patients. Here, we provide an overview of approaches currently under clinical investigation for optical surgical navigation and offer our perspective on upcoming strategies.

KEYWORDS:

Image guidance; Oncology; Optical navigation; Probes; Surgery

PMID:
28271367
PMCID:
PMC5567813
DOI:
10.1007/s11307-017-1054-1
[Indexed for MEDLINE]
Free PMC Article

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