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J Allergy Clin Immunol. 2017 Aug;140(2):584-587.e8. doi: 10.1016/j.jaci.2016.11.049. Epub 2017 Mar 1.

HMGB1 is upregulated in the airways in asthma and potentiates airway smooth muscle contraction via TLR4.

Author information

1
Institute for Lung Health, Department of Infection, Immunity & Inflammation, Glenfield Hospital, University of Leicester, Leicester, United Kingdom.
2
San Raffaele University and Scientific Institute and HMGBiotech s.r.l., Milan, Italy.
3
Department of Molecular and Cell Biology, University of Leicester, Leicester, United Kingdom.
4
Institute for Lung Health, Department of Infection, Immunity & Inflammation, Glenfield Hospital, University of Leicester, Leicester, United Kingdom. Electronic address: rms4@le.ac.uk.

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