Send to

Choose Destination
J Allergy Clin Immunol. 2017 Apr;139(4):1099-1110. doi: 10.1016/j.jaci.2017.02.007. Epub 2017 Feb 28.

The microbiome in allergic disease: Current understanding and future opportunities-2017 PRACTALL document of the American Academy of Allergy, Asthma & Immunology and the European Academy of Allergy and Clinical Immunology.

Author information

Division of Pulmonary and Critical Care, Department of Internal Medicine, University of Michigan, Ann Arbor, Mich.
Service de Pneumologie, Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland.
Division of Allergy and Immunology, Departments of Pediatrics and Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY.
Molecular Immunology, Swiss Institute of Allergy and Asthma Research, University of Zurich, Davos, Switzerland.
Division of Allergy and Immunology, Department of Pediatrics, National Jewish Health, Denver, Colo.
Food Allergy Referral Centre Veneto Region, Department of Women and Child Health, Padua General University Hospital, Padua, Italy.
Department of Laboratory Medicine, Clinical Center, National Institutes of Health, Bethesda, Md. Electronic address:


PRACTALL is a joint initiative of the American Academy of Allergy, Asthma & Immunology and the European Academy of Allergy and Clinical Immunology to provide shared evidence-based recommendations on cutting-edge topics in the field of allergy and immunology. PRACTALL 2017 is focused on what has been established regarding the role of the microbiome in patients with asthma, atopic dermatitis, and food allergy. This is complemented by outlining important knowledge gaps regarding its role in allergic disease and delineating strategies necessary to fill these gaps. In addition, a review of progress in approaches used to manipulate the microbiome will be addressed, identifying what has and has not worked to serve as a baseline for future directions to intervene in allergic disease development, progression, or both.


Microbiome; asthma; atopic dermatitis; dysbiosis; food allergy; microbiota; prebiotic; probiotic; systems biology

[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for Elsevier Science Icon for PubMed Central
Loading ...
Support Center