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Cell Stem Cell. 2017 Mar 2;20(3):291-292. doi: 10.1016/j.stem.2017.02.008.

Unsaturated Fatty Acids Maintain Cancer Cell Stemness.

Author information

1
Department of Obstetrics and Gynecology/Section of Gynecologic Oncology, The University of Chicago, Chicago, IL 60637, USA.
2
Department of Obstetrics and Gynecology/Section of Gynecologic Oncology, The University of Chicago, Chicago, IL 60637, USA. Electronic address: elengyel@uchicago.edu.

Abstract

Investigation of the metabolic regulation of cancer stem cells is an emerging field that offers promising approaches for identifying and targeting recalcitrant stem cell populations. In this issue of Cell Stem Cell, Li et al. (2017) indicate that increased lipid desaturation is essential to stem-like characteristics in ovarian cancer cells.

PMID:
28257705
PMCID:
PMC5956908
DOI:
10.1016/j.stem.2017.02.008
[Indexed for MEDLINE]
Free PMC Article

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