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Adv Exp Med Biol. 2017;980:19-25. doi: 10.1007/5584_2017_8.

Hospital Morbidity Database for Epidemiological Studies on Churg-Strauss Syndrome.

Author information

1
Department of Social Medicine and Public Health, Medical University of Warsaw, Oczki Str. 3, 02-007, Warsaw, Poland. kanecki@mp.pl.
2
Department of Social Medicine and Public Health, Medical University of Warsaw, Oczki Str. 3, 02-007, Warsaw, Poland.
3
National Institute of Public Health - National Institute of Hygiene, Chocimska 24, 00-971, Warsaw, Poland.

Abstract

Churg-Strauss syndrome or more accurately eosinophilic granulomatosis with polyangiitis (EGPA) is a small-vessel necrotizing vasculitis with a characteristic late-onset allergic rhinitis and asthma. The use of hospital morbidity database is an important element of the epidemiological analysis of this rare disease. The present study was undertaken to assess the incidence of EGPA and factors related to its epidemiology in Poland; the first analysis of the kind in Poland, enabling a comparison in the European context. This is a retrospective, population-based study using hospital discharge records with EGPA diagnosis, collected for a National Institute of Public Health survey covering the period from 2008 to 2013. The group consisted of 344 patients (206 females and 138 males) with the first-time hospitalization for EGPA. The major findings are that the annual incidence of EGPA in Poland was 1.5 per million (95% confidence intervals: 1.2-1.8), with the point prevalence of 8.8 per million at the end of 2013. A greater incidence of EGPA was observed in the regions with urban predominance. We conclude that discharge records may be a useful element of epidemiological studies on EGPA.

KEYWORDS:

ANCA-associated; Disease prevalence; Eosinophilic granulomatosis; Epidemiology; Morbidity; Polyangiitis; Vasculitis

PMID:
28255916
DOI:
10.1007/5584_2017_8
[Indexed for MEDLINE]

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