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J Res Med Sci. 2016 Nov 7;21:116. doi: 10.4103/1735-1995.193507. eCollection 2016.

The effect of a 10-week high-intensity interval training and ginger consumption on inflammatory indices contributing to atherosclerosis in overweight women.

Author information

1
Department of Physical Education and Sport Sciences, Faculty of Educational Sciences and Psychology, University of Sistan and Baluchestan, Zahedan, Iran.
2
Department of Exercise Physiology, Faculty of Sport Sciences, University of Birjand, Birjand, Iran.
3
Department of Cardiology, Atherosclerosis and Coronary Artery Research Centre, Birjand University of Medical Sciences, Birjand, Iran.
4
Department of Biochemistry, Faculty of Medicine, Gonabad University of Medical Sciences, Gonabad, Iran.

Abstract

BACKGROUND:

Most of the cardiovascular diseases can be prevented by doing regular physical exercises and using herbal supplements. The present study is aimed at assessing ginger supplement and high-intensity interval training (HIIT) on inflammatory indices contributing to atherosclerosis in overweight women.

MATERIALS AND METHODS:

The present study is a randomized, experimental, and controlled one in which thirty healthy overweight women aged 20-30 years were randomly divided into three equal groups, namely, ginger, ginger + HIIT, and placebo + HIIT. The training groups performed high-intensity interval exercises (i.e. 40-m maximal shuttle run) for ten consecutive weeks. The supplement groups daily took 3 g of ginger pills and the third group took placebo.

RESULTS:

Paired t-test revealed a significant decrease in the density of type 1 monocytes chemo tactic protein (MCP-1) in HIIT + ginger (P = 0.026) and HIIT + placebo (P = 0.001) groups. Besides, maximum aerobic capacity in the two training groups significantly increased P = 0.002 and P = 0.000, respectively. In spite of this, analysis of variance showed no significant differences in three groups regarding the three indices such as intercellular adhesion molecule-1 (ICAM-1) (P = 0.093), MCP-1(P = 0.075), and serum interleukin-10 (IL-10) (P = 0.164).

CONCLUSION:

A 10-week intensive interval exercise, by itself or together with ginger supplement, improved MCP-1 and maximum oxygen consumption in overweight women, without any significant effect on soluble ICAM-1 and IL-10. These findings indicate the relative and efficient role of HIIT in overweight women without the necessity to combine with ginger as an antioxidant/anti-inflammatory supplement.

KEYWORDS:

Ginger; high-intensity interval exercise; intercellular adhesion molecule-1; interleukin-10; monocyte chemotactic protein-1; overweight

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