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Med Devices (Auckl). 2017 Feb 17;10:29-41. doi: 10.2147/MDER.S124098. eCollection 2017.

Metered Cryospray™: a novel uniform, controlled, and consistent in vivo application of liquid nitrogen cryogenic spray.

Author information

1
CSA Medical Inc., Lexington, MA.
2
Pathology Laboratory for Translational Medicine, West Virginia University, Morgantown, WV, USA.

Abstract

In this article, a novel cryotherapy approach using a uniform, controlled, and consistent in vivo application of liquid nitrogen (LN2) spray as a Metered Cryospray (MCS) process is described. Although MCS may be used for many potential clinical applications, this paper focuses on the development that led to the controlled and consistent delivery of radial LN2 cryogen spray in order to generate a uniform circumferential effect and how the amount of MCS can be adapted to specifically ablate targeted diseases within a patient's lumen such as an airway or esophagus.

KEYWORDS:

LN2 spray cryotherapy; Metered Cryospray™; cryoablation; rejuvenative healing

Conflict of interest statement

Disclosure All authors except James E Coad, MD, are employees of CSA Medical Inc. Dr Coad is a paid consultant of CSA Medical Inc. The authors report no other conflicts of interest in this work.

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