The Phospholamban Journey 4 Decades After Setting Out for Ithaka

Circ Res. 2017 Mar 3;120(5):781-783. doi: 10.1161/CIRCRESAHA.116.310007.

Authors

Evangelia G Kranias¹, Roger J Hajjar²

Affiliations

¹ From the Department of Pharmacology and Cell Biophysics, University of Cincinnati College of Medicine, OH (E.G.K.); and Cardiovascular Research Center, Department of Cardiology, Icahn School of Medicine at Mount Sinai, New York, NY (R.J.H.). litsa.kranias@uc.edu.
² From the Department of Pharmacology and Cell Biophysics, University of Cincinnati College of Medicine, OH (E.G.K.); and Cardiovascular Research Center, Department of Cardiology, Icahn School of Medicine at Mount Sinai, New York, NY (R.J.H.).

No abstract available

Keywords: catecholamines; cell survival; heart failure; mutation; sarcoplasmic reticulum.

Publication types

Historical Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't

MeSH terms

Animals
Arrhythmias, Cardiac / genetics
Calcium Signaling
Calcium-Binding Proteins / antagonists & inhibitors
Calcium-Binding Proteins / genetics
Calcium-Binding Proteins / history*
Calcium-Binding Proteins / physiology
Cardiomyopathy, Dilated / genetics
Heart Failure / drug therapy
History, 20th Century
History, 21st Century
Humans
Induced Pluripotent Stem Cells / transplantation
Mice
Mice, Transgenic
Multiprotein Complexes / physiology
Mutation
Phosphorylation
Protein Processing, Post-Translational
Rabbits
Sarcoplasmic Reticulum Calcium-Transporting ATPases / physiology

Substances

Calcium-Binding Proteins
Multiprotein Complexes
phospholamban
Sarcoplasmic Reticulum Calcium-Transporting ATPases

Supplementary concepts

Familial dilated cardiomyopathy

Grants and funding