Abstract
We report a case of a 48-year-old male patient with "krokodil" drug-related osteonecrosis of both jaws. Patient history included 1.5 years of "krokodil" use, with 8-month drug withdrawal prior to surgery. The patient was HCV positive. On the maxilla, sequestrectomy was performed. On the mandible, sequestrectomy was combined with bone resection. From ramus to ramus, segmental defect was formed, which was not reconstructed with any method. Post-operative follow-up period was 3 years and no disease recurrence was noted. On 3-year post-operative orthopantomogram, newly formed mandibular bone was found. This phenomenon shows that spontaneous bone formation is possible after mandible segmental resection in osteonecrosis patients.
Keywords:
Bone formation; Jaw osteonecrosis; Jaw resection; “Krokodil” drug.
MeSH terms
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Analgesics, Opioid / toxicity
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Armenia
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Bone Regeneration / physiology*
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Codeine / analogs & derivatives*
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Codeine / toxicity
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Follow-Up Studies
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Humans
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Male
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Mandible / diagnostic imaging
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Mandible / physiopathology
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Mandible / surgery
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Mandibular Diseases / chemically induced*
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Mandibular Diseases / diagnostic imaging
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Mandibular Diseases / physiopathology
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Mandibular Diseases / surgery*
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Maxilla / diagnostic imaging
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Maxilla / physiopathology
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Maxilla / surgery
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Maxillary Diseases / chemically induced*
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Maxillary Diseases / diagnostic imaging
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Maxillary Diseases / physiopathology
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Maxillary Diseases / surgery
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Middle Aged
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Narcotics / adverse effects
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Osteonecrosis / chemically induced*
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Osteonecrosis / diagnostic imaging
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Osteonecrosis / physiopathology
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Osteonecrosis / surgery*
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Radiography, Panoramic
Substances
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Analgesics, Opioid
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Narcotics
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desomorphine
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Codeine