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J Crit Care. 2017 Jun;39:115-123. doi: 10.1016/j.jcrc.2017.02.032. Epub 2017 Feb 24.

Predicting risk for portal vein thrombosis in acute pancreatitis patients: A comparison of radical basis function artificial neural network and logistic regression models.

Author information

1
Surgical Intensive Care Unit (SICU), Department of General Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing 210002, China.
2
School of mechanical engineering, Nanjing University of Science and Technology, Nanjing 210094, China.
3
Surgical Intensive Care Unit (SICU), Department of General Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing 210002, China. Electronic address: chamskuler@163.com.
4
Department of General Surgery, Bayi Hospital Affiliated Nanjing University of Chinese Medicine/The 81st Hospital of P.L.A., Nanjing 210002, China.

Abstract

OBJECTIVE:

To construct a radical basis function (RBF) artificial neural networks (ANNs) model to predict the incidence of acute pancreatitis (AP)-induced portal vein thrombosis.

METHODS:

The analysis included 353 patients with AP who had admitted between January 2011 and December 2015. RBF ANNs model and logistic regression model were constructed based on eleven factors relevant to AP respectively. Statistical indexes were used to evaluate the value of the prediction in two models.

RESULTS:

The predict sensitivity, specificity, positive predictive value, negative predictive value and accuracy by RBF ANNs model for PVT were 73.3%, 91.4%, 68.8%, 93.0% and 87.7%, respectively. There were significant differences between the RBF ANNs and logistic regression models in these parameters (P<0.05). In addition, a comparison of the area under receiver operating characteristic curves of the two models showed a statistically significant difference (P<0.05).

CONCLUSION:

The RBF ANNs model is more likely to predict the occurrence of PVT induced by AP than logistic regression model. D-dimer, AMY, Hct and PT were important prediction factors of approval for AP-induced PVT.

KEYWORDS:

Logistic regression; Neural network; Pancreatitis; Radical basis function; Thrombosis

PMID:
28246056
DOI:
10.1016/j.jcrc.2017.02.032
[Indexed for MEDLINE]

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