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J Cutan Pathol. 2017 Jun;44(6):578-581. doi: 10.1111/cup.12924. Epub 2017 Mar 23.

Late latent mucinous syphilis mimicking connective tissue disease.

Author information

1
Ackerman Academy of Dermatopathology, New York, New York.
2
East Valley Dermatology Center, Chandler, Arizona.
3
University of Arizona, Department of Medicine, Division of Dermatology, Tucson, Arizona.
4
Dermpath Diagnostics, Tucson, Arizona.

Abstract

As evidenced by the Centers for Disease Control and Prevention (CDC) statistics, syphilis is yet again on the rise. It is known as the great mimicker because of its variable symptoms and how frequently it can be confused with other diseases. The different stages of syphilis (primary, secondary, latent, late latent and tertiary) are discussed. We describe a new histopathologic pattern of syphilis, one that mimics connective tissue disease and can represent a diagnostic pitfall. In this time and age, when syphilis is rising especially among the men who have sex with men subgroup, it is important to keep a high index of suspicion of syphilis even when clinically and histopathologically the findings on first glance may not appear characteristic.

KEYWORDS:

dermatomyositis; lupus; mucin; spirochete; syphilis

PMID:
28244118
DOI:
10.1111/cup.12924
[Indexed for MEDLINE]

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