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Clin Exp Rheumatol. 2017 May-Jun;35 Suppl 105(3):28-34. Epub 2017 Feb 24.

Fibromyalgia prevalence and associated factors in primary Sjögren's syndrome patients in a large cohort from the Spanish Society of Rheumatology registry (SJOGRENSER).

Author information

1
Rheumatology Department, Hospital General Hospitalet-Moisès Broggi, Barcelona, Spain. vtorrente@hsjdbcn.org.
2
Rheumatology Department, Hospital General Hospitalet-Moisès Broggi, Barcelona, Spain.
3
Research Unit, Spanish Society of Rheumatology, Madrid, Spain.
4
Rheumatology Department, Hospital Infanta Sofía, San Sebastián de los Reyes, Madrid,Spain.
5
Rheumatology Department, Hospital Universitario Puerta de Hierro Majadahonda, Madrid, Spain.
6
Rheumatology Department, Hospital Marqués de Valdecilla, Santander, Spain.
7
Rheumatology Department, Hospital Germans Trias i Pujol, Badalona, Spain.
8
Rheumatology Department, Hospital Marina Baixa, Alicante, Spain.

Abstract

OBJECTIVES:

To assess fibromyalgia (FM) prevalence in a large cohort of primary Sjögren's syndrome patients (pSS) from a National Database.

METHODS:

Data included in the national retrospective register of pSS patients of the Spanish Society of Rheumatology (SJOGRENSER) were analysed.

RESULTS:

437 pSS patients were included and a 14.6% of FM prevalence was found. FM-pSS patients significantly showed more constitutional, fatigue and arthralgia symptoms, splenomegaly, genital, skin and ear involvement and dyslipidaemia (p<0.05), as well as higher ESSPRI and SSDAI scores (p<0.01). Several symptomatic treatments were more frequently used in FM-pSS patients. No differences were observed in laboratory markers, imaging techniques or histologic inflammatory findings. Patients with FM showed statistically more fatigue than pSS without FM. In the multivariate logistic regression analysis several features were associated to pSS-FM patients.

CONCLUSIONS:

We show data on a reliable prevalence of FM in pSS patients and its multiple associated factors along with the presence of higher disease activity scores than patients who did not show FM. The presence of fatigue, arthralgia, constitutional symptoms and dyslipidaemia were more likely to coexist in pSS-FM patients.

PMID:
28240585
[Indexed for MEDLINE]

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