Acne necrotica (necrotizing lymphocytic folliculitis): An enigmatic and under-recognised dermatosis

Australas J Dermatol. 2018 Feb;59(1):e53-e58. doi: 10.1111/ajd.12592. Epub 2017 Feb 27.

Abstract

Acne necrotica is a disorder of adults of obscure aetiology, featuring repeated cropping of inflammatory papulonodules which rapidly necrotise, leaving varying degrees of superficial scarring with pathological features in early lesions of a necrotising lymphocytic folliculitis. A perceived diminishing interest in this entity in recent years prompted a prospective study of patients presenting to a dermatology practice over a 3-year period to reassess the prevalence of this disorder in general dermatological patients, leading to the identification of 47 patients (35 female) with features of acne necrotica, with histopathology undertaken in atypical cases. We identified the importance of the recognition of primary lesions (1-2 mm umbilicated erythematous papules), often difficult to find in excoriated areas, as being paramount in the diagnosis both clinically and histologically in our study, which reveals a significantly more prevalent and clinically diverse disorder than featured in previous textbook and academic journal descriptions.

Keywords: acne necrotica; dermal hypersensitivity; doxycycline; excoriation; necrotising lymphocytic folliculitis; neurosis; pruritus; urticarial dermatitis.

MeSH terms

  • Acne Vulgaris / diagnosis*
  • Acne Vulgaris / epidemiology
  • Acne Vulgaris / pathology*
  • Adult
  • Aged
  • Aged, 80 and over
  • Australia / epidemiology
  • Female
  • Folliculitis / diagnosis*
  • Folliculitis / epidemiology
  • Folliculitis / pathology*
  • Humans
  • Male
  • Middle Aged
  • Necrosis
  • Skin / pathology*
  • Young Adult