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Intest Res. 2017 Jan;15(1):38-67. doi: 10.5217/ir.2017.15.1.38. Epub 2017 Jan 31.

Second Korean guidelines for the management of Crohn's disease.

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Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.
Department of Internal Medicine, University of Ulsan College of Medicine, Seoul, Korea.
Department of Internal Medicine, Inje University College of Medicine Ilsan Paik Hospital, Goyang, Korea.
Department of Internal Medicine, Sungkyunkwan University School of Medicine, Seoul, Korea.
Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.
Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea.
Department of Internal Medicine, The Catholic University of Korea College of Medicine, Suwon, Korea.
Department of Surgery, Hallym University College of Medicine, Chuncheon, Korea.
Center for Preventive Medicine and Public Health, Seoul National University Bundang Hospital, Seongnam, Korea.


Crohn's disease (CD) is a chronic, progressive, and disabling inflammatory bowel disease (IBD) with an uncertain etiopathogenesis. CD can involve any site of the gastrointestinal tract from the mouth to the anus, and is associated with serious complications, such as bowel strictures, perforations, and fistula formation. The incidence and prevalence rates of CD in Korea are still lower compared with those in Western countries, but they have been rapidly increasing during the recent decades. Although there are no definitive curative modalities for CD, various medical and surgical therapies have been applied for the treatment of this disease. Concerning CD management, there have been substantial discrepancies among clinicians according to their personal experience and preference. To suggest recommendable approaches to the diverse problems of CD and to minimize the variations in treatment among physicians, guidelines for the management of CD were first published in 2012 by the IBD Study Group of the Korean Association for the Study of Intestinal Diseases. These are the revised guidelines based on updated evidence, accumulated since 2012. These guidelines were developed by using mainly adaptation methods, and encompass induction and maintenance treatment of CD, treatment based on disease location, treatment of CD complications, including stricture and fistula, surgical treatment, and prevention of postoperative recurrence. These are the second Korean guidelines for the management of CD and will be continuously revised as new evidence is collected.


Crohn disease; Guideline; Management

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