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Nat Rev Nephrol. 2017 Apr;13(4):241-257. doi: 10.1038/nrneph.2017.2. Epub 2017 Feb 27.

Acute kidney disease and renal recovery: consensus report of the Acute Disease Quality Initiative (ADQI) 16 Workgroup.

Author information

1
Department of Medicine, Veterans Affairs Medical Center, Washington DC, USA.
2
Australian and New Zealand Intensive Care Research Centre, Monash University, Australia.
3
Department of Medicine, University of Florida, USA.
4
Division of Nephrology and Hypertension, Cincinnati Children's Hospital Medical Center, USA.
5
Division of Nephrology and Hypertension, Vanderbilt University School of Medicine, USA.
6
Division of Critical Care Medicine, Faculty of Medicine and Dentistry, University of Alberta, Canada.
7
Department of Medicine, University of California San Diego, USA.
8
UCSD Medical Center, University of California San Diego, USA.
9
Department of Nephrology, Prince of Wales Hospital and Clinical School, University of New South Wales, Australia.
10
Surrey County Hospital, UK.
11
University of Pittsburgh School of Pharmacy, USA.
12
Intensive Care Unit, Ghent University Hospital, Ghent University, Belgium.
13
Department of Medicine, University of Chicago, USA.
14
Divisions of Nephrology and Critical Care, Departments of Medicine and Anesthesia, University of California, USA.
15
UCD Health Sciences Centre, University College Dublin, Ireland.
16
Division of Nephrology, Department of Medicine, Keck School of Medicine, University of Southern California, USA.
17
Guy's &St Thomas' NHS Foundation Hospital, Department of Intensive Care, UK.
18
Renal Section, VA Pittsburgh Healthcare System, USA.
19
Renal-Electrolyte Division, University of Pittsburgh, USA.
20
Division of Nephrology, University of Virginia, USA.
21
Division of Nephrology, St. Michaels Hospital and the University of Toronto, Canada.
22
University Hospital M√ľnster, Germany.
23
Department of Nephrology, Dialysis and Transplantation, San Bortolo Hospital, International Renal Research Institute of Vicenza, Italy.
24
Center for Critical Care Nephrology, Department of Critical Care Medicine, University of Pittsburgh, USA.

Abstract

Consensus definitions have been reached for both acute kidney injury (AKI) and chronic kidney disease (CKD) and these definitions are now routinely used in research and clinical practice. The KDIGO guideline defines AKI as an abrupt decrease in kidney function occurring over 7 days or less, whereas CKD is defined by the persistence of kidney disease for a period of >90 days. AKI and CKD are increasingly recognized as related entities and in some instances probably represent a continuum of the disease process. For patients in whom pathophysiologic processes are ongoing, the term acute kidney disease (AKD) has been proposed to define the course of disease after AKI; however, definitions of AKD and strategies for the management of patients with AKD are not currently available. In this consensus statement, the Acute Disease Quality Initiative (ADQI) proposes definitions, staging criteria for AKD, and strategies for the management of affected patients. We also make recommendations for areas of future research, which aim to improve understanding of the underlying processes and improve outcomes for patients with AKD.

PMID:
28239173
DOI:
10.1038/nrneph.2017.2
[Indexed for MEDLINE]

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