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Arch Neurol. 1987 Nov;44(11):1204-5.

Mollaret's meningitis associated with acute Epstein-Barr virus mononucleosis.

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  • 1Department of Medicine, University of Rochester, School of Medicine and Dentistry, NY 14642.


A 19-year-old man developed recurrent aseptic meningitis (Mollaret's meningitis) during the course of acute Epstein-Barr virus infectious mononucleosis. Serum contained heterophil antibody and Epstein-Barr virus-specific antibodies characteristic of acute infection. Seven brief episodes of aseptic meningitis were documented over the following one-year period, in each case with a polymorphonuclear pleocytosis in the cerebrospinal fluid. Acute infection with Epstein-Barr virus, or subsequent reactivation of virus, may account for some cases of Mollaret's meningitis.

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