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Arch Pathol Lab Med. 1987 Dec;111(12):1123-9.

Opportunistic cancers in patients with immunodeficiency syndromes.

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Department of Pathology, University of Nebraska Medical Center, Omaha 68105-1065.

Erratum in

  • Arch Pathol Lab Med 1988 Mar;112(3):234.


Patients with inherited or acquired immunodeficiency disorders are vulnerable to a broad spectrum of opportunistic infectious diseases, but a narrow spectrum of malignancies. These malignancies--B-cell lymphomas, Kaposi's sarcomas, and squamous cell carcinomas--are likely due to failure of immune surveillance to recognize virally transformed target cells. The evidence for this hypothesis is substantial regarding Epstein-Barr virus-induced lymphoproliferative lesions in immunodeficient patients.

[Indexed for MEDLINE]

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