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Euro Surveill. 2017 Feb 16;22(7). doi: 10.2807/1560-7917.ES.2017.22.7.30465.

Combined effectiveness of prior and current season influenza vaccination in northern Spain: 2016/17 mid-season analysis.

Author information

1
Instituto de Salud Pública de Navarra, IdiSNA - Navarre Institute for Health Research, Pamplona, Spain.
2
CIBER Epidemiología y Salud Pública (CIBERESP), Spain.
3
Complejo Hospitalario de Navarra, IdiSNA - Navarre Institute for Health Research, Pamplona, Spain.
4
Centro Nacional de Microbiología (WHO National Influenza Centre - Madrid), Instituto de Salud Carlos III, Majadahonda, Spain.
5
The members of these networks are listed at the end of the article.

Abstract

The 2016/17 mid-season vaccine effectiveness estimate against influenza A(H3N2) was 15% (95% confidence interval: -11 to 35) in Navarre. Comparing to individuals unvaccinated in the current and four prior seasons, effectiveness was 24% for current and 3-4 prior doses, 61% for current and 1-2 prior doses, 42% for only current vaccination, and 58% for 3-4 prior doses. This suggests moderate effectiveness for different combinations of vaccination in the current and prior seasons.

KEYWORDS:

case control study; influenza; influenza vaccine; influenza-like illness; repeated vaccination; vaccine effectiveness

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