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Mol Phylogenet Evol. 2017 Apr;109:404-408. doi: 10.1016/j.ympev.2017.02.001. Epub 2017 Feb 12.

The conserved phylogeny of blood microbiome.

Author information

1
Department of Information Technology, Indian Institute of Engineering Science and Technology, Shibpur, Howrah 711103, India. Electronic address: malaybhattacharyya@it.iiests.ac.in.
2
Department of Information Technology, Indian Institute of Engineering Science and Technology, Shibpur, Howrah 711103, India.
3
Department of Physiology, Medical College of Wisconsin, Milwaukee, WI 53226, USA.

Abstract

The proliferation and intensification of diseases have forced every researcher to take actions for a robust understanding of the organisms. This demands deep knowledge about the cells and tissues in an organ and its entire surroundings, more precisely the microbiome community which involves viruses, bacteria, archaea, among others. They play an important role in the function of our body, and act both as a deterrent as well as shelter for diseases. Therefore, it is pertinent to study the relation within the microbiome in a human body. In this work, we analyze the sequence data provided through the Human Microbiome Project to explore evolutionary relations within blood microbiome. The objective is to analyze the common proteins present in the different microbes in the blood and find their phylogeny. The analysis of the phylogenetic relation between these species provides important insights about the conservedness of phylogeny of blood microbiome. Interestingly, the co-existence of five of those common proteins is observed in human too.

KEYWORDS:

Blood microbiome; Co-existence analysis; Microbiome evolution; Phylogeny

PMID:
28216014
DOI:
10.1016/j.ympev.2017.02.001
[Indexed for MEDLINE]

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