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Rev Med Inst Mex Seguro Soc. 2017;55 Suppl 1:S34-S43.

[Five-year survival analysis in patients with penile cancer].

[Article in Spanish; Abstract available in Spanish from the publisher]

Author information

1
División de Investigación en Salud, Hospital de Traumatología y Ortopedia, Centro Médico Nacional "Manuel Ávila Camacho", Instituto Mexicano del Seguro Social, Puebla, Puebla, México. dralmoja@hotmail.com.

Abstract

in English, Spanish

BACKGROUND:

Short-term survival of penile cancer is poor. The objective was to describe the 5-years penile cancer survival.

METHODS:

Retrospective cohort study. We included patients with penile cancer managed surgically from 2010 to 2014. Descriptive statistics were used for socio-demographic variables and the Kaplan-Meier estimator for survival function.

RESULTS:

We studied 22 patients with a mean age of 64.95 years and a time of evolution of 25 months after the diagnosis. 68.2% of patients smoked or had human papillomavirus (HPV); they all presented phimosis; 72.7% had pain in the penis and the groin area; 81.8% had palpable lymph nodes and 45.5% lesions ≥ 3 cm; 86.3% were diagnosed in clinical stage IIIa. 59.1% underwent partial penectomy and 86.4% had squamous cell variety. 40.9% of patients died six months after the surgery. 66% of the smokers presented metastasis; all of the patients that smoked and had HPV infection had neurovascular invasion and died; 83.3% of the patients (n = 6) who underwent partial penectomy and positive lymph node dissection due to metastases died. The 5-years mortality of patients with penile cancer was 40.9%.

CONCLUSION:

Tobacco use and HPV increase morbidity and mortality in patients with penile cancer; lesions greater than 5 cm are more common in smokers. The size of the lesion increases with the delay in treatment.

KEYWORDS:

Epidemiology; Mortality; Penile cancer; Survival

PMID:
28212473
[Indexed for MEDLINE]

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