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Iran Red Crescent Med J. 2016 Oct 2;18(11):e38728. doi: 10.5812/ircmj.38728. eCollection 2016 Nov.

Perioperative Concerns for Profound Metabolic Alkalosis During Kidney Transplantation: A Case Report.

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Department of Anesthesiology and Pain Medicine, Gachon University, Gil Medical Center, Incheon, South Korea.



Profound metabolic alkalosis is an uncommon consideration for the anesthetic management of kidney transplantation. Serum total carbon dioxide content and complex electrolyte abnormalities might be important diagnostic clues for the presence of metabolic alkalosis in the absence of arterial blood gas analysis.


A 34-year-old female visited Gachon University Gil Medical Center, Incheon, South Korea during year 2015. She experienced aggravated renal function due to chronic hypokalemia and severe hypochloremic metabolic alkalosis, induced by laxative abuse, and underwent ABO incompatible kidney transplantation. Serum total carbon dioxide content remained high (about 60 mEq/L) over eight months of monthly follow-up prior to kidney transplantation.


The authors described their anesthetic experience of profound metabolic alkalosis with complex electrolyte abnormalities and provided a review of relevant literature.


Alkalosis; Hypoventilation; Kidney Transplantation

Conflict of interest statement

Conflict of Interest:The authors declare that there were no conflicts of interest.

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