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FEBS Lett. 1987 Sep 28;222(1):75-8.

A new approach for EPR detection of hydroxyl radicals by reaction with sterically hindered cyclic amines and oxygen.

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1
Division of Contaminant Chemistry, Center for Food Safety and Applied Nutrition, Washington, DC 20204.

Abstract

Sterically hindered cyclic amines react with hydroxyl radicals in the presence of oxygen to yield stable nitroxide radicals which can be detected by EPR. This reaction provides a nonconventional spin-trapping tool for detection of hydroxyl radicals.

PMID:
2820800
[Indexed for MEDLINE]
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