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Soc Psychiatry Psychiatr Epidemiol. 2017 Apr;52(4):435-443. doi: 10.1007/s00127-017-1337-5. Epub 2017 Feb 8.

Life course persistent and adolescence limited conduct disorder in a nationally representative US sample: prevalence, predictors, and outcomes.

Author information

1
Center for Clinical and Translational Research, Virginia Commonwealth University, Richmond, VA, USA. mooreaa2@vcu.edu.
2
Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, VA, USA. mooreaa2@vcu.edu.
3
Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, VA, USA.
4
Department of Human and Molecular Genetics, Virginia Commonwealth University, Richmond, VA, USA.
5
Department of Psychiatry, Virginia Commonwealth University, Richmond, VA, USA.
6
Department of Family Medicine and Population Health, Division of Epidemiology, Virginia Commonwealth University, Richmond, VA, USA.
7
Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, MI, USA.

Abstract

PURPOSE:

The course of conduct disorder (CD) is heterogeneous. Moffitt proposed the heuristic of life course persistent (LCP) and adolescence limited (AL) to differentiate etiologically distinct forms of antisocial behavior (AB), each with distinct predictors and consequences, although a few studies have assessed this demarcation within the context of CD. The objective of this study was to apply Moffitt's taxonomy in a nationally representative US sample to investigate the prevalence, predictors, and outcomes of LCP and AL CD.

METHODS:

Data come from the Collaborative Psychiatric Epidemiology Studies, a set of population-based nationally representative cross-sectional surveys (N = 20,130). Predictors included harsh discipline, maternal and paternal closeness, poverty in childhood, history of learning disability, parental deviance, and nativity. Outcomes included substance use, employment status, education attainment, marital status, income level, and self-rated mental and physical health.

RESULTS:

The prevalence of LCP and AL CD was 0.5 and 4.6%, respectively, for females, and 1.9 and 5.1%, respectively, for males. Low childhood SES [Odds Ratio (OR) = 3.49], lack of maternal closeness (OR = 2.50), and history of harsh discipline (OR = 2.17) increased odds of LCP group membership. The LCP group had higher odds of developing substance use disorders (OR = 2.00) relative to AL.

CONCLUSIONS:

LCP CD is more strongly influenced by childhood environment and confers increased odds for substance use problems in adulthood relative to AL CD.

KEYWORDS:

Adolescence limited; Conduct disorder; Epidemiology; Life course persistent; Moffitt’s taxonomy

PMID:
28180930
PMCID:
PMC5382064
DOI:
10.1007/s00127-017-1337-5
[Indexed for MEDLINE]
Free PMC Article

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