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Anticancer Res. 1989 Jul-Aug;9(4):1101-3.

A case of squamous cell lung carcinoma with tetrasomy 7 and chromosome 1 C-band polymorphism.

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Institute of Anatomy and Cytology, Odense University, Denmark.


Hyperdiploidy was observed in about 20% of the metaphase cells from a short-term culture of a squamous cell carcinoma of the lung. C-, G-and R-banding of both tumour and lymphocyte preparations showed constitutional C-band abnormalities in both homologues of chromosome No. 1. Based on these banding studies, the tumour karyotype was determined as: 48, XY, inv(1)(pter----q11::q21----qter), -1, -11, +7, +7, +19, +del(1) (pter----q11::q21----qter).

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