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Int J Biol Macromol. 2017 May;98:366-378. doi: 10.1016/j.ijbiomac.2017.02.002. Epub 2017 Feb 3.

Investigation on Curcumin nanocomposite for wound dressing.

Author information

1
Department of Nanotechnology, SRM University, Kattankulathur, Tamil Nadu, India. Electronic address: gdevanandvenkatasubbu@gmail.com.
2
Department of Nanotechnology, SRM University, Kattankulathur, Tamil Nadu, India.

Abstract

Curcuma longa (turmeric) has a long history of use in medicine as a treatment for inflammatory conditions. The primary active constituent of turmeric and the one responsible for its vibrant yellow color is curcumin. Curcumin is used for treatment of wound and inflammation. It had antimicrobial and antioxidant property. It has low intrinsic toxicity and magnificent properties like with comparatively lesser side-effects. Cotton cloth is one of the most successful wound dressings which utilize the intrinsic properties of cotton fibers. Modern wound dressings, however, require other properties such as antibacterial and moisture maintaining capabilities. In this study, conventional cotton cloth was coated with Curcumin composite for achieving modern wound dressing properties. Curcumin nanocomposite is characterized. The results show that coated cotton cloth with Curcumin nanocomposite has increased drying time (74%) and water absorbency (50%). Furthermore, they show antibacterial efficiency against bacterial species present in wounds.

KEYWORDS:

Antibacterial activity; Composite; Curcumin; Water holding time; Wound dressing

PMID:
28167107
DOI:
10.1016/j.ijbiomac.2017.02.002
[Indexed for MEDLINE]

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