Format

Send to

Choose Destination
Biology (Basel). 2017 Feb 3;6(1). pii: E8. doi: 10.3390/biology6010008.

Metaphase Spindle Assembly.

Author information

1
Laboratory of Chemistry and Cell Biology, the Rockefeller University, New York, NY 10065, USA. kapoor@mail.rockefeller.edu.

Abstract

A microtubule-based bipolar spindle is required for error-free chromosome segregation during cell division. In this review I discuss the molecular mechanisms required for the assembly of this dynamic micrometer-scale structure in animal cells.

KEYWORDS:

cell division; chromosome; dynein; kinesin; metaphase; microtubules; mitosis

Supplemental Content

Full text links

Icon for Multidisciplinary Digital Publishing Institute (MDPI) Icon for PubMed Central
Loading ...
Support Center