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Biomed Res Int. 2017;2017:4650182. doi: 10.1155/2017/4650182. Epub 2017 Jan 9.

Conservative Nonhormonal Options for the Treatment of Male Infertility: Antibiotics, Anti-Inflammatory Drugs, and Antioxidants.

Author information

1
Department of Clinical and Experimental Medicine, University of Catania, Catania, Italy.
2
Department of Surgery, Urology Section, University of Catania, Catania, Italy.

Abstract

The nonhormonal medical treatment can be divided into empirical, when the cause has not been identified, and nonempirical, if the pathogenic mechanism causing male infertility can be solved or ameliorated. The empirical nonhormonal medical treatment has been proposed for patients with idiopathic or noncurable oligoasthenoteratozoospermia and for normozoospermic infertile patients. Anti-inflammatory, fibrinolytic, and antioxidant compounds, oligo elements, and vitamin supplementation may be prescribed. Infection, inflammation, and/or increased oxidative stress often require a specific treatment with antibiotics, anti-inflammatory drugs, and/or antioxidants. Combined therapies can contribute to improve sperm quality.

PMID:
28164122
PMCID:
PMC5253172
DOI:
10.1155/2017/4650182
[Indexed for MEDLINE]
Free PMC Article

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