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Curr Vasc Pharmacol. 2017;15(5):416-429. doi: 10.2174/1570161115666170202161719.

Ethnic and Geographical Differences in Ischaemic Stroke Among Young Adults.

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Istanbul Tıp Fakultesi, Nöroloji AD, Capa, Fatih, Istanbul. Turkey.
Department of Neurology, Helsinki University Central Hospital, Helsinki. Finland.
Department of Neurology, Istanbul University, Istanbul Faculty of Medicine, Istanbul. Turkey.



Ischaemic stroke in young adults encompasses approximately 5 - 15% of all ischaemic strokes, depending on the selected upper age limit. The key features of the disease, including incidence, risk factors, underlying causes, mortality, outcomes, as well as long-term risks of recurrent events are different from those for elderly patients. There is also evidence indicating that these characteristics may differ ethnically and geographically. It is clinically important to recognize such differences not only for correct diagnosis and treatment, but also for introducing accurate preventive measures. Ethnic differences may stem from several factors, including genetic influence, and necessitate different approaches, such as personalized diagnostic work-up based on patient characteristics.


In this review, we summarize and discuss the existing data on the geographic and ethnic differential characteristics of young adult ischaemic stroke.


Adult; aetiology; epidemiology; ethnic groups; geographic factors; middle aged; mortality; outcome studies; risk factors; stroke; young adult

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