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Nutr J. 2017 Jan 31;16(1):7. doi: 10.1186/s12937-017-0232-y.

Relationship between coffee consumption and stroke risk in Korean population: the Health Examinees (HEXA) Study.

Author information

1
Department of Nutritional Science and Food Management, Ewha Womans University, 52 Ewhayeodae-gil, 03760, Seodaemun-gu, Seoul, South Korea.
2
Department of Physical Education, College of Education, Chung-Ang University, 06974, Seoul, Republic of Korea.
3
Department of Nutritional Science and Food Management, Ewha Womans University, 52 Ewhayeodae-gil, 03760, Seodaemun-gu, Seoul, South Korea. yuri.kim@ewha.ac.kr.

Abstract

BACKGROUND:

Although coffee consumption is increasing rapidly, the results of previous studies regarding the association between coffee consumption and stroke risk have been conflicting. This was a multi-center cross-sectional study that aimed to evaluate the relationship between coffee consumption and stroke risk in Korean population.

METHODS:

Data were obtained from the Health Examinees (HEXA) Study, which involved 146,830 individuals aged 40-69 years. Coffee consumption was categorized as none, < 1 cup/day, 1 to < 3 cups/day, and ≥ 3 cups/day. We used logistic regression models to examine the association between coffee consumption and the risk of stroke while controlling for potential confounders and performed subgroup analyses.

RESULTS:

After adjusting for age and various possible confounders, high coffee consumption was associated with a 38% lower odds ratio for stroke in women (none vs. ≥ 3 cups/day: OR, 0.62; 95% CI 0.47-0.81; P for trend < 0.0001). No significant association was found in men (none vs. ≥ 3 cups/day: OR, 0.84; 95% CI, 0.66-1.07; P for trend = 0.1515). In analyses stratified by covariates, an inverse association between coffee consumption and stroke risk was most evident among healthy women who were younger, non-obese, non-hypertensive, non-diabetic, non-smokers, and non-alcohol drinkers.

CONCLUSION:

Our results suggest that higher coffee consumption may have protective benefits with regards to stroke risk in middle-aged Korean women.

KEYWORDS:

HEXA; Korean; coffee; stroke

PMID:
28143499
PMCID:
PMC5282694
DOI:
10.1186/s12937-017-0232-y
[Indexed for MEDLINE]
Free PMC Article

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