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Zh Nevrol Psikhiatr Im S S Korsakova. 2016;116(12):112-113. doi: 10.17116/jnevro2016116121112-113.

[Treatment of asthenoneurotic disorders in children].

[Article in Russian; Abstract available in Russian from the publisher]

Author information

1
Russian Medical Academy of Postgraduate Education, Moscow, Russia; Z.A.Bashlaeva Children's City Clinical Hospital, Moscow, Russia.
2
Russian Medical Academy of Postgraduate Education, Moscow, Russia.

Abstract

in English, Russian, Russian

AIM:

To evaluate the efficacy of cogitum in the treatment of asthenoneurotic disorders in children after bacterial meningitis (BM) or brain injury (BI).

MATERIAL AND METHODS:

Twenty-four patients were examined. Group 1 included 14 patients with BM, 8 boys and 6 girls, aged 7 - 12 years, mean age 9,91 ± 1,71 years; group 2 consisted of 10 patients with BI, 6 boys and 4 girls, aged 7-12 years, mean age 10,4 ± 2,36 years. All patients received cogitum in dose of 250- 500 mg daily during 8 weeks. Neurological and neuropsychological (Bourdon's test, Luria's tests) examinations, EEG, MRI were performed before and after treatment.

RESULTS AND CONCLUSION:

The study of cognitive functions showed a decrease in the accuracy and speed during performance of Bourdon's and Luria's tests. After the beginning of treatment with cogitum, 80% of the patients in both groups demonstrated a significant improvement in the accuracy of Bourdon's test (р<0,01) and verbal retention (р<0,001). Repeated EEG (3-6 months after treatment) showed the distinct theta- , alpha-, beta- rhythms and clear zonal differences. Given a spectrum of clinical effects of cogitum, the authors recommend it for active use in pediatric practice.

[Indexed for MEDLINE]

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