Send to

Choose Destination
Zh Nevrol Psikhiatr Im S S Korsakova. 2016;116(12):112-113. doi: 10.17116/jnevro2016116121112-113.

[Treatment of asthenoneurotic disorders in children].

[Article in Russian; Abstract available in Russian from the publisher]

Author information

Russian Medical Academy of Postgraduate Education, Moscow, Russia; Z.A.Bashlaeva Children's City Clinical Hospital, Moscow, Russia.
Russian Medical Academy of Postgraduate Education, Moscow, Russia.


in English, Russian, Russian


To evaluate the efficacy of cogitum in the treatment of asthenoneurotic disorders in children after bacterial meningitis (BM) or brain injury (BI).


Twenty-four patients were examined. Group 1 included 14 patients with BM, 8 boys and 6 girls, aged 7 - 12 years, mean age 9,91 ± 1,71 years; group 2 consisted of 10 patients with BI, 6 boys and 4 girls, aged 7-12 years, mean age 10,4 ± 2,36 years. All patients received cogitum in dose of 250- 500 mg daily during 8 weeks. Neurological and neuropsychological (Bourdon's test, Luria's tests) examinations, EEG, MRI were performed before and after treatment.


The study of cognitive functions showed a decrease in the accuracy and speed during performance of Bourdon's and Luria's tests. After the beginning of treatment with cogitum, 80% of the patients in both groups demonstrated a significant improvement in the accuracy of Bourdon's test (р<0,01) and verbal retention (р<0,001). Repeated EEG (3-6 months after treatment) showed the distinct theta- , alpha-, beta- rhythms and clear zonal differences. Given a spectrum of clinical effects of cogitum, the authors recommend it for active use in pediatric practice.

[Indexed for MEDLINE]

Supplemental Content

Loading ...
Support Center