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Trends Microbiol. 2017 Mar;25(3):169-170. doi: 10.1016/j.tim.2017.01.003. Epub 2017 Jan 27.

A New Way to Beat Intestinal Pathogens.

Author information

1
Department of Molecular, Cellular, and Developmental Biology, University of Colorado Boulder, Boulder, CO, USA. Electronic address: detweile@Colorado.EDU.

Abstract

In the gastrointestinal tract, the tug of war for iron may provide a new way to vaccinate. Recent work shows that immunizing mice with siderophores (small molecules that microbes produce to capture iron) foils pathogen colonization and may instead allow a commensal to expand.

PMID:
28139374
PMCID:
PMC5336408
DOI:
10.1016/j.tim.2017.01.003
[Indexed for MEDLINE]
Free PMC Article

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