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J Genomics. 2017 Jan 12;5:1-3. doi: 10.7150/jgen.17904. eCollection 2017.

First Draft Genome Sequence of the Dourine Causative Agent: Trypanosoma Equiperdum Strain OVI.

Author information

  • 1ANSES, Dozulé Laboratory for Equine Diseases, Bacteriology and Parasitology Unit, 14430 Goustranville, France.
  • 2Université de Poitiers, Laboratoire Ecologie et Biologie des Interactions, UMR CNRS 7267, 5 rue Albert Turpain, TSA 51106, 86073 Poitiers, France.
  • 3Wellcome Trust Sanger Institute, Genome Campus, Hinxton, Cambridge, CB10 1SA, United Kingdom.
  • 4ANSES, Lyon Laboratory, Plateforme d'Expérimentation Animale, 31 avenue Tony Garnier, 69007 Lyon, France.
  • 5Institute of Tropical Medicine, Department of Biomedical Sciences, Nationalestraat 155, B-2000 Antwerp, Belgium.
  • 6ANSES, Dozulé Laboratory for Equine Diseases, 14430 Goustranville, France.
  • 7ANSES, Dozulé Laboratory for Equine Diseases, Bacteriology and Parasitology Unit, 14430 Goustranville, France.; Current address: ANSES, Laboratoire de Lyon, Unité Epidémiologie, 31 avenue Tony Garnier, 69007 Lyon, France.

Abstract

Trypanosoma equiperdum is the causative agent of dourine, a sexually-transmitted infection of horses. This parasite belongs to the subgenus Trypanozoon that also includes the agent of sleeping sickness (Trypanosoma brucei) and surra (Trypanosoma evansi). We herein report the genome sequence of a T. equiperdum strain OVI, isolated from a horse in South-Africa in 1976. This is the first genome sequence of the T. equiperdum species, and its availability will provide important insights for future studies on genetic classification of the subgenus Trypanozoon.

KEYWORDS:

Dourine; Trypanosoma equiperdum; Trypanozoon.; Whole-genome sequencing

PMID:
28138343
PMCID:
PMC5278650
DOI:
10.7150/jgen.17904
[PubMed - in process]
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