Format

Send to

Choose Destination
Ann Biol Clin (Paris). 2017 Feb 1;75(1):87-91. doi: 10.1684/abc.2016.1212.

An Addison disease revealed with a serious hyponatremia.

Author information

1
Laboratoire.
2
Unité d'endocrinologie.
3
Service de réanimation.
4
Service d'accueil urgence, Centre Hospitalier de la Région d'Annecy Genevois, Metz-Tessy, Pringy, France.

Abstract

We present the case of an Addison's disease revealed by a serious hyponatremia. The serum concentration of ACTH and 21-hydroxylase antibodies were increased and lead to the diagnosis. The cortisol blood level was lowered but required to take into account the stress induced by the hospitalisation of the patient. Addison's disease is characterized by the destruction of the adrenal cortex. Autoimmune adrenalitis is the main cause of adrenal insufficiency. Treatment involves normalisation of sodium concentration and corticosteroids replacement. With a good patient compliance, the survival rate of Addisonian patient is similar to that of the normal population. Management of patient requires vigilance because of the occurrence of others autoimmunes diseases during patient life.

KEYWORDS:

Addison disease; anti-21hydroxylase antibodies; cortisol concentration-ACTH; hyponatremia

PMID:
28132947
DOI:
10.1684/abc.2016.1212
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for John Libbey Eurotext
Loading ...
Support Center