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Bratisl Lek Listy. 2016;117(11):677-680. doi: 10.4149/BLL_2016_130.

The effect of mad honey on testosterone levels of male rats.

Abstract

OBJECTIVE:

We aimed to investigate the effect of mad honey on sexual performance.

BACKGROUND:

In traditional medicine in Turkey, mad honey is used to improve appetite, to heighten mental alertness, to reduce joint pain, to eliminate gastrointestinal system pains and to increase sexual performance.

METHODS:

In this experimental animal study eighteen Sprague Dawley male rats were randomized into three groups, a control group, a normal honey group and a mad honey group. Rats in the treatment groups were given a daily dose of 80 mg/kg normal honey or mad honey throughout the 30-day study period. Total testosterone, free testosterone, FSH, LH, estradiol, and progesterone levels were subsequently investigated from blood sera on day 30.

RESULTS:

Comparison of blood total testosterone levels among the groups revealed significantly higher levels in the mad honey group compared to the normal honey and control groups (p = 0.006, p = 0.00). Free testosterone levels were also significantly higher in the mad honey group than in the normal honey and control groups (p = 0.023, p = 0.01). No statistically significant differences were determined for other hormonal measurements.

CONCLUSIONS:

This study revealed a significant increase in both total and free testosterone levels in mad-honey group (Tab. 1, Fig. 2, Ref. 16).

KEYWORDS:

grayanotoxin; mad honey; sexual performance testosterone.; traditional medicine

PMID:
28125895
DOI:
10.4149/BLL_2016_130
[Indexed for MEDLINE]

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