Send to

Choose Destination
Doc Ophthalmol. 2017 Feb;134(1):1-9. doi: 10.1007/s10633-017-9573-2. Epub 2017 Jan 21.

ISCEV Standard for clinical electro-oculography (2017 update).

Author information

Discipline of Optometry and Vision Science, Flinders University, Adelaide, Australia.
Department of Ophthalmology, University Medical Center Freiburg, Freiburg, Germany.
College of Optometry, University of Houston, Houston, TX, USA.
Ophthalmic Genetics and Visual Function Branch, National Eye Institute, Bethesda, MD, USA.
Institute of Ophthalmology, University College London, London, UK.
Moorfields Eye Hospital, London, UK.


The clinical electro-oculogram (EOG) is an electrophysiological test of the outer retina and retinal pigment epithelium (RPE) in which changes in the electrical potential across the RPE are recorded during successive periods of dark and light adaptation. This document presents the 2017 EOG Standard from the International Society for Clinical Electrophysiology of Vision (ISCEV: ). This standard has been reorganized and updated to include an explanation of the mechanism of the EOG, but without substantive changes to the testing protocol from the previous version published in 2011. It describes methods for recording the EOG in clinical applications and gives detailed guidance on technical requirements, practical issues and reporting of results with the main clinical measure (the Arden ratio) now termed the light peak:dark trough ratio. The standard is intended to promote consistent quality of testing and reporting within and between clinical centers.


Arden ratio; Clinical electrophysiology; Electro-oculogram (EOG); Fast oscillation (FO); ISCEV Standards; Light adaptation; Light peak:dark trough ratio; Retinal pigment epithelium (RPE)

[Indexed for MEDLINE]
Free PMC Article

Conflict of interest statement

The authors declare no conflict of interests. Statement of human rights This article does not contain any studies with human participants performed by any of the authors. Statement on the welfare of animals This article does not contain any studies with animals performed by any of the authors. Informed consent As this article does not contain any studies with human participants performed directly by any of the authors, the concept of informed consent is not applicable.

Supplemental Content

Full text links

Icon for Springer Icon for PubMed Central
Loading ...
Support Center