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Complement Ther Clin Pract. 2017 Feb;26:21-25. doi: 10.1016/j.ctcp.2016.11.006. Epub 2016 Nov 12.

The effect of yoga training on enhancement of Adrenocorticotropic hormone (ACTH) and cortisol levels in female patients with multiple sclerosis.

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Department of Exercise Physiology, Marvdasht Branch, Islamic Azad University, Marvdasht, Iran.
Department of Exercise Physiology, Shiraz Branch, Islamic Azad University, Shiraz, Iran. Electronic address:


The effect of 8 weeks yoga training on cortisol and Adrenocorticotropic hormone (ACTH) levels in female patients with Multiple Sclerosis (MS) is examined. Twenty four MS female patients with Expanded Disability Status Scale (EDSS) 1 to 5.5 participated in this study as the subject. The participants were divided into control (n = 10) or training group (n = 14) randomly. Training group performed 90 min yoga training per session, 3 days a week for 8 weeks. Assessments include body composition measurement and blood sampling 48 h before first session and 48 h after the intervention. The results demonstrated that ACTH increased and cortisol decreased compared to the control group (P < 0.05); In conclusion, it seems that yoga training modulates ACTH level in concomitant with reduction in cortisol level in female patients with MS.


Adrenocorticotropic hormone(ACTH); Cortisol; Multiple sclerosis; Randomized controlled trials; Yoga

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