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Nature. 2017 Jan 18;541(7637):302-310. doi: 10.1038/nature21347.

Tracing the peopling of the world through genomics.

Author information

1
Department of Integrative Biology, University of California, Berkeley, Berkeley, California 94720, USA.
2
Department of Statistics, University of California, Berkeley, Berkeley, California 942720, USA.
3
Centre for GeoGenetics, Natural History Museum of Denmark, University of Copenhagen, 1350 Copenhagen K, Denmark.
4
Department of Genome Sciences, University of Washington, Seattle, Washington 98195-5065, USA.
5
Department of Organismal Biology, Uppsala University, 752 36 Uppsala, Sweden.
6
Department of Genetics, Stanford University, Stanford, California 94305, USA.
7
Department of Biology, Stanford University, Stanford, California 94305, USA.
8
Howard Hughes Medical Institute, Stanford University, Stanford, California 94305, USA.
9
Department of Genetics, University of Pennsylvania, Pennsylvania 19104, USA.
10
Department of Biology, University of Pennsylvania, Pennsylvania 19104, USA.
11
Department of Zoology, University of Cambridge, Cambridge CB2 3EJ, UK.
12
Wellcome Trust Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, CB10 1SA, UK.

Abstract

Advances in the sequencing and the analysis of the genomes of both modern and ancient peoples have facilitated a number of breakthroughs in our understanding of human evolutionary history. These include the discovery of interbreeding between anatomically modern humans and extinct hominins; the development of an increasingly detailed description of the complex dispersal of modern humans out of Africa and their population expansion worldwide; and the characterization of many of the genetic adaptions of humans to local environmental conditions. Our interpretation of the evolutionary history and adaptation of humans is being transformed by analyses of these new genomic data.

PMID:
28102248
PMCID:
PMC5772775
DOI:
10.1038/nature21347
[Indexed for MEDLINE]
Free PMC Article

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