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Oral Surg Oral Med Oral Pathol Oral Radiol. 2017 Mar;123(3):358-364. doi: 10.1016/j.oooo.2016.10.018. Epub 2016 Nov 1.

Idiopathic gingival papillokeratosis with crypt formation, a report of 7 cases of a previously undescribed entity: possible unusual oral epithelial nevus?

Author information

1
Division of Oral Pathology, Boston University Henry M. Goldman School of Dental Medicine, Boston, MA, USA; Center for Oral Pathology, StrataDx, Lexington, MA, USA. Electronic address: vnoonan@bu.edu.
2
Center for Oral Pathology, StrataDx, Lexington, MA, USA; Department of Oral Medicine, Infection, and Immunity, Harvard University School of Dental Medicine, Boston, MA, USA.
3
Division of Oral Pathology, Boston University Henry M. Goldman School of Dental Medicine, Boston, MA, USA.
4
Center for Oral Pathology, StrataDx, Lexington, MA, USA.

Abstract

We report 7 cases of hitherto undescribed keratotic papillary plaques of uncertain etiology involving the gingiva. All 7 cases presented on the anterior maxillary attached gingiva of patients in the second decade. The lesions were asymptomatic and 86% (6 of 7 cases) presented in a bilateral symmetric distribution. Microscopically, the lesions exhibited parakeratosis and papillary acanthosis with parakeratin-filled crypts. No specific etiology such as a factitial habit or a common exogenous agent has been identified. The possibility of a developmental etiology such as an oral epithelial nevus cannot be entirely excluded. We propose the descriptive term idiopathic gingival papillokeratosis with crypt formation (IGPC) for this condition.

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PMID:
28089460
DOI:
10.1016/j.oooo.2016.10.018
[Indexed for MEDLINE]

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