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Int J Biol Macromol. 2017 Apr;97:228-237. doi: 10.1016/j.ijbiomac.2017.01.040. Epub 2017 Jan 10.

Structures, biological activities, and industrial applications of the polysaccharides from Hericium erinaceus (Lion's Mane) mushroom: A review.

Author information

1
Hong-Hui Hospital, Xi'an Jiaotong University College of Medicine, Xi'an 710054, PR China; Key Laboratory of Resource Biology and Biotechnology in Western China (Northwest University), Ministry of Education, Xi'an 710069, PR China. Electronic address: hxrhist@163.com.
2
Key Laboratory of Resource Biology and Biotechnology in Western China (Northwest University), Ministry of Education, Xi'an 710069, PR China.
3
Hong-Hui Hospital, Xi'an Jiaotong University College of Medicine, Xi'an 710054, PR China.
4
Hong-Hui Hospital, Xi'an Jiaotong University College of Medicine, Xi'an 710054, PR China. Electronic address: huanglhlab@163.com.

Abstract

Hericium erinaceus (Bull.) Pers., also known as Yamabushitake, Houtou and Lion's Mane, is capable of fortifying the spleen and nourishing the stomach, tranquilizing the mind, and fighting cancer. Over the past decade, it has been demonstrated that H. erinaceus polysaccharides possess various promising bioactivities, including antitumor and immunomodulation, anti-gastric ulcer, neuroprotection and neuroregeneration, anti-oxidation and hepatoprotection, anti-hyperlipidemia, anti-hyperglycemia, anti-fatigue and anti-aging. The purpose of the present review is to provide systematically reorganized information on extraction and purification, structure characteristics, biological activities, and industrial applications of H. erinaceus polysaccharides to support their therapeutic potentials and sanitarian functions.

KEYWORDS:

Hericium erinaceus; Industrial applications; Polysaccharides

PMID:
28087447
DOI:
10.1016/j.ijbiomac.2017.01.040
[Indexed for MEDLINE]

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