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Curr Opin Biotechnol. 2017 Apr;44:130-137. doi: 10.1016/j.copbio.2016.12.004. Epub 2017 Jan 10.

Rationalising vitamin B6 biofortification in crop plants.

Author information

1
Department of Botany and Plant Biology, University of Geneva, Geneva, Switzerland.
2
Department of Biology, ETH Zurich, Zurich, Switzerland.
3
Gembloux Agro-Bio Tech, University of Liège, Gembloux, Belgium.
4
Department of Botany and Plant Biology, University of Geneva, Geneva, Switzerland. Electronic address: teresa.fitzpatrick@unige.ch.

Abstract

Vitamin B6 encompasses a group of related compounds (vitamers) that can only be biosynthesised de novo by plants and microorganisms. Enzymatic cofactor and antioxidant functions for vitamin B6 are established in all kingdoms. Human vitamin B6 dietary insufficiency or genetic defects in B6 vitamer interconversion result in various neurological and inflammatory pathologies with several populations at-risk or marginal for vitamin B6 status. Three (rice, wheat and cassava) of the world's top five staple crops do not meet the recommended dietary allowance for vitamin B6, when consumed as a major proportion of the diet. In addition, controlled enhancement of the appropriate B6 vitamer in crops has the potential to confer stress resistance. Thus, crop biofortification strategies represent an opportunity to reduce the risk of deficiency in populations with limited diet diversity and quality, as well as improving stress tolerance.

PMID:
28086191
DOI:
10.1016/j.copbio.2016.12.004
[Indexed for MEDLINE]

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