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Chem Commun (Camb). 2017 Feb 4;53(10):1611-1614. doi: 10.1039/c6cc09781b. Epub 2017 Jan 13.

PSMA-targeted contrast agents for intraoperative imaging of prostate cancer.

Author information

1
Gordon Center for Medical Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, MA 02114, USA. hchoi12@mgh.harvard.edu.

Abstract

Prostate-specific membrane antigen (PSMA) can serve as a molecular cell surface target for the detection and treatment of prostate cancer. Near-infrared (NIR) fluorescence imaging enables highly sensitive, rapid, and non-radioactive imaging of PSMA, though specific targeting still remains a challenge because no optimized contrast agents exist.

PMID:
28085163
PMCID:
PMC5728657
DOI:
10.1039/c6cc09781b
[Indexed for MEDLINE]
Free PMC Article

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